A neutrophil elastase inhibitor reduces cigarette smoke-induced remodelling of lung vessels
نویسندگان
چکیده
منابع مشابه
A neutrophil elastase inhibitor reduces cigarette smoke-induced remodelling of lung vessels.
Cigarette smoking produces pulmonary hypertension (PHT) through unknown mechanisms. In animal models acute smoke exposure induces cell proliferation in the small arteries adjacent to the alveolar ducts, and chronic exposure results in muscularisation of these vessels, with changes related to the development of PHT. Studies indicate that serine-elastase inhibitors can prevent experimental monocr...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2003
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.03.00095703